| Bioactivity | Nicarbazin-d8 is deuterium labeled Nicarbazin. Nicarbazin is an effective anticoccidial agent for chickens[1]. |
| Invitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| Name | Nicarbazin-d8 |
| Formula | C19H10D8N6O6 |
| Molar Mass | 434.43 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Ott, W. H., et al. Biological Studies on Nicarbazin, a New Anticoccidial Agent. Poultry Science. 1956. 35(6), 1355–1367. [3]. CUCKLER AC, et al. The effect of nicarbazin on the development of immunity to avian coccidia. J Parasitol. 1956 Dec;42(6):593-607. |