| Bioactivity | Niacin (Vitamin B3) is an orally active water-soluble B3 vitamin that is an essential nutrient for humans. Niacin (Vitamin B3) plays a key role in energy metabolism, cell signaling cascades regulating gene expression and apoptosis. Niacin (Vitamin B3) is also used in the study of cardiovascular diseases[1][2]. | ||||||||||||
| Invitro | Niacin (0-900 μM, 42 hours) significantly increases GSH levels and decreases ROS levels, and affects the expression of genes related to apoptosis and lipid metabolism[1].Niacin (0-40 μM, 24 hours) can inhibit cancer invasive activity at low dose but with no influence on proliferation[2]. RT-PCR[1] Cell Line: | ||||||||||||
| Name | Niacin | ||||||||||||
| CAS | 59-67-6 | ||||||||||||
| Formula | C6H5NO2 | ||||||||||||
| Molar Mass | 123.11 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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