| Bioactivity | Nevirapine quinone methide is an active metabolite of Nevirapine, serving as a non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infection and AIDS. Nevirapine quinone methide is associated with severe skin and liver injuries due to its metabolic activation pathways. Nevirapine quinone methide has been shown to inhibit CYP3A4, which could contribute to its hepatic toxicity. |
| CAS | 1061160-22-2 |
| Formula | C15H12N4O |
| Molar Mass | 264.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Synthesis and evaluation of nevirapine analogs to study the metabolic activation of nevirapine |
Nevirapine quinone methide
CAS: 1061160-22-2 F: C15H12N4O W: 264.28
Nevirapine quinone methide is an active metabolite of Nevirapine, serving as a non-nucleoside reverse transcriptase inhi
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