| Bioactivity | Nevadistinel (NYX-458; NYX-3054) is a positive allosteric modulator of N-methyl-D-aspartate (NMDA) receptor. Nevadistinel can be used to inhibit cognitive impairment associated with neurodegenerative diseases, such as mild cognitive impairment, mild Alzheimer's disease, Parkinson's disease, Lewy body disease[1]. |
| Target | NMDA receptor |
| Name | Nevadistinel |
| CAS | 2181816-92-0 |
| Formula | C15H18N2O3 |
| Molar Mass | 274.32 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Khan, et al. Preparation of spiro-lactam as NMDA receptor modulators for the treatment of depression and related disorders. World Intellectual Property Organization, WO2018026798 A1. 2018-02-08. |