| Bioactivity | Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (PR3) with IC50 values of 4.91 μM and 20.69 μM, respectively. Neutrophil elastase inhibitor 5 can be used in the study of neutrophil inflammatory diseases[1]. |
| Target | IC50: 4.91 μM (HNE); 20.69 μM (PR3). |
| Name | Neutrophil elastase inhibitor 5 |
| Formula | C24H18N4O4 |
| Molar Mass | 426.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hwang TL, et al. Design and synthesis of sirtinol analogs as human neutrophil elastase inhibitors. Bioorg Med Chem Lett. 2023 Nov 7;97:129544 |
Neutrophil elastase inhibitor 5
CAS: F: C24H18N4O4 W: 426.42
Neutrophil elastase inhibitor 5 (compound 29) is a dual inhibitor of HNE (human neutrophil elastase) and proteinase 3 (P
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