| Bioactivity | Neutrophil elastase inhibitor 1 (Compound 5b) is a competitive, pseudoirreversible inhibitor for neutrophil elastase with an IC50 of 7 nM[1]. |
| Target | IC50: 7 nM (Neutrophil elastase), 1.9 μM (Thrombin), 0.066 μM (chymotrypsin), 6.6 μM (urokinase) |
| CAS | 1448314-31-5 |
| Formula | C16H11N3O |
| Molar Mass | 261.28 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Crocetti L, et al., Optimization of N-benzoylindazole derivatives as inhibitors of human neutrophil elastase. J Med Chem. 2013 Aug 8;56(15):6259-72. |
Neutrophil elastase inhibitor 1
CAS: 1448314-31-5 F: C16H11N3O W: 261.28
Neutrophil elastase inhibitor 1 (Compound 5b) is a competitive, pseudoirreversible inhibitor for neutrophil elastase wit
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This product is for research use only, not for human use. We do not sell to patients.