| Bioactivity | Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. | ||||||
| Invitro | Receptor internalization induced by Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density. The receptor downregulation in response to high extracellular concentrations of the peptide has been described for Neurotensin (NT) in HT-29 cells and in rat primary cultured neurons. Reappearance of the receptors on the cell surface is also different[1]. | ||||||
| Name | Neurotensin(8-13) | ||||||
| CAS | 60482-95-3 | ||||||
| Sequence | Arg-Arg-Pro-Tyr-Ile-Leu | ||||||
| Shortening | RRPYIL | ||||||
| Formula | C38H64N12O8 | ||||||
| Molar Mass | 816.99 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |