| Bioactivity | Neuropeptide Y (human) free acid upregulates the adhesiveness of human endothelial cells for leukocytes. Neuropeptide Y belongs to the pancreatic polypeptide family, plays an important role in circadian rhythms, neurogenesis, and neuroprotection, nociception, feeding behavior, energy regulation, neuronal excitability, emotion, cognition, and stress response[1][2]. |
| Invitro | Neuropeptide Y (human) free acid 抑制 SK-N-MC 细胞中 Isoproterenol (HY-B0468), Dopamine, Vasoactive intestinal peptide, Cholera toxin, Forskolin (HY-15371) 诱导的 cyclic AMP 累积[3]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> Neuropeptide Y (human) (free acid) 相关抗体: |
| CAS | 99575-89-0 |
| Sequence | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr |
| Shortening | YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQ |
| Formula | C189H284N54O58S |
| Molar Mass | 4272.67 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cajado et al. Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms. Toxicol Sci. 2014 Dec;142(2):418-26. [2]. Sung CP, et al. Neuropeptide Y upregulates the adhesiveness of human endothelial cells for leukocytes. Circ Res. 1991 Jan;68(1):314-8. [3]. Gordon EA, et al. Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line. J Neurochem. 1990 Aug;55(2):506-13. |
Neuropeptide Y (human) (free acid)
CAS: 99575-89-0 F: C189H284N54O58S W: 4272.67
Neuropeptide Y (human) free acid upregulates the adhesiveness of human endothelial cells for leukocytes. Neuropeptide Y
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