PeptideDB

Neuromedin B

CAS: 87096-84-2 F: C52H73N15O12S W: 1132.29

Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.
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Bioactivity Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.
Invitro Potency to stimulate contraction of rat uterine smooth muscle, that is used as bioassay for isolation of Neuromedin B (NMB), is compared with Bombesin (BN). The relative potency, calculated on molar basis by taking BN as 100, is 48% for GRP and 4.9% for NMB. NMB also has contractile activity on rat stomach strip, but the potency (ratio of peptide concentration required to elicit 50% maximum response; EC50) is only 5% of BN (EC50 of BN/EC50 of NMB) and about 10% of GRP (EC50 of GRP/ EC50 of NMB)[1].
Name Neuromedin B
CAS 87096-84-2
Formula C52H73N15O12S
Molar Mass 1132.29
Transport Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)