| Bioactivity | Neuraminidase-IN-2 is an anti-influenza compounds with IC50 values of 0.28, 0.27, 11.50, 0.089 and 23.44 µM for H1N1, 09H1N1, H3N2, H5N1 and H5N2, respectively. Neuraminidase-IN-2 has antiviral activity and low cytotoxicity[1]. |
| In Vivo | Neuraminidase-IN-2 (Compound 5c) (1 g/kg；灌胃；单剂量) 对小鼠毒性较低，不显著增加小鼠的体重[1]。 |
| Name | Neuraminidase-IN-2 |
| CAS | 2599015-44-6 |
| Formula | C29H38N2O6 |
| Molar Mass | 510.62 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jia R, et al. Discovery of highly potent and selective influenza virus neuraminidase inhibitors targeting 150-cavity. Eur J Med Chem. 2021 Feb 15;212:113097. |
Neuraminidase-IN-2
CAS: 2599015-44-6 F: C29H38N2O6 W: 510.62
Neuraminidase-IN-2 is an anti-influenza compounds with IC50 values of 0.28, 0.27, 11.50, 0.089 and 23.44 µM for H1N1, 0
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This product is for research use only, not for human use. We do not sell to patients.