Bioactivity | Neuraminidase-IN-15 is an inhibitor of neuraminidase. Neuraminidase-IN-15 inhibits the activity of La Sota Clone 30 NDV-HN with an IC50 value of 0.06 µM. Neuraminidase-IN-15 can be used for the study of Newcastle disease virus (NDV) [1]. |
Invitro | Neuraminidase-IN-15 (Compound 23) (0.0001-100 µM) 以剂量依赖性方式减少了 Vero 细胞中新城疫病毒 (NDV) La Sota 载量[1]。Neuraminidase-IN-15 抑制 Vero 细胞中 NDV La Sota 的结合与释放,IC50 值分别为 24 µM 和 0.13 µM[1]。 |
Name | Neuraminidase-IN-15 |
Formula | C19H21F3N2O8 |
Molar Mass | 462.37 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rota P, et al. Design, Synthesis, and Antiviral Evaluation of Sialic Acid Derivatives as Inhibitors of Newcastle Disease Virus Hemagglutinin-Neuraminidase: A Translational Study on Human Parainfluenza Viruses. ACS Infect Dis. 2023 Mar 10;9(3):617-630. |