Bioactivity | Neuraminidase-IN-14 is an inhibitor of neuraminidase. Neuraminidase-IN-14 inhibits the activity of La Sota Clone 30 NDV-HN with an IC50 value of 0.20 µM. Neuraminidase-IN-14 can be used for research on Newcastle disease virus (NDV) infection[1]. |
Invitro | Neuraminidase-IN-14 (Compound 24) (0.0001-100 µM) 以剂量依赖性方式减少了 Vero 细胞中新城疫病毒 (NDV) La Sota 载量[1]。Neuraminidase-IN-14 抑制 Vero 细胞中 NDV La Sota 的结合与释放,IC50 值分别为 15 µM 和 0.17 µM[1]。 |
Name | Neuraminidase-IN-14 |
Formula | C13H14F6N2O8 |
Molar Mass | 440.25 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Rota P, et al. Design, Synthesis, and Antiviral Evaluation of Sialic Acid Derivatives as Inhibitors of Newcastle Disease Virus Hemagglutinin-Neuraminidase: A Translational Study on Human Parainfluenza Viruses. ACS Infect Dis. 2023 Mar 10;9(3):617-630. |