Neuraminidase-IN-13_product_DataBase

Bioactivity	Neuraminidase-IN-13 (Compound 10) is a neuraminidase inhibitor with antiviral activity and low cytotoxicity. Neuraminidase-IN-13 significantly inhibits NDV infection of Vero cells by preventing the release of viral particles from infected cells[1].
Invitro	Neuraminidase-IN-13 抑制 NDV La Sota 菌株中的斑块形成，IC50 值为 0.06 μM[1]。Neuraminidase-IN-13 抑制病毒增殖，IC50 为 0.04 μM[1]。Neuraminidase-IN-13 对细胞无毒性，CC50值大于2500 μM[1]。Neuraminidase-IN-13 抑制病毒结合 Vero 细胞，IC50 为 4 μM[1]。Neuraminidase-IN-13 抑制 Vero 细胞中病毒释放，IC50 值为 0.09 μM[1]。
Name	Neuraminidase-IN-13
CAS	2222067-23-2
Formula	C13H13F7N4O7
Molar Mass	470.25
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Rota P, et al. Design, Synthesis, and Antiviral Evaluation of Sialic Acid Derivatives as Inhibitors of Newcastle Disease Virus Hemagglutinin-Neuraminidase: A Translational Study on Human Parainfluenza Viruses. ACS Infect Dis. 2023 Mar 10;9(3):617-630.

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