| Bioactivity | Nequinate, a quinoline compound, is an anticoccidial agent against cecal coccidiosis (Eimeria tenella) infections[1]. Nequinate inhibits xanthine oxidoreductase (XOD) activity[2]. |
| Invitro | Xanthine oxidase (XOD) is a successful and safe drug target for lowering lower serum urate (sUA) levels , it plays an important role in the catabolism of purineNequinate shows an inhibition of 12.0% to inhibit XOD activities[2]. |
| Name | Nequinate |
| CAS | 13997-19-8 |
| Formula | C22H23NO4 |
| Molar Mass | 365.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. D K McLoughlin, et al.Efficacy of Nequinate Against Thirteen Strains of Eimeria Tenella and the Development of a Nequinate-Resistant Strain.Avian Dis. Oct-Dec 1973;17(4):717-21. [2]. Yanfen Niu, et al. Old Drug, New Indication: Olsalazine Sodium Reduced Serum Uric Acid Levels in Mice via Inhibiting Xanthine Oxidoreductase Activity. J Pharmacol Sci. 2017 Nov;135(3):114-120. |