Bioactivity | Neo Spiramycin I-d3is the deuterium labeledNeo Spiramycin I(HY-143623)[1]. Neo Spiramycin I (NSPI) is the active metabolite of Spiramycin (SPI) with antimicrobial activity. Neo Spiramycin is widely used in veterinary medicine[2]. |
Invitro | 氢、碳和其他元素的稳定重同位素已被纳入药物分子中,主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注,因为它可能影响药物的药代动力学和代谢谱[1]。 |
Name | Neo Spiramycin I-dC |
Formula | C36H59D3N2O11 |
Molar Mass | 701.90 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Saleh H, et al. Validation of hplc-uv multi-residue method for the simultaneous determination of tetracycline, oxytetracycline, spiramycin and neospiramycin in raw milk[J]. Food Analytical Methods, 2021, 14: 36-43. |