| Bioactivity | Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action[1]. Nemifitide diTFA is a peptide analog of melanocyte-inhibiting factor (MIF)[2]. Nemifitide diTFA can cross the blood-brain barrier[3]. | ||||||
| Invitro | Nemifitide diTFA (INN 00835 diTFA) and its active metabolite (M1) bind at micromolar concentrations to several receptors including the 5-HT2A, 5-HT2C, melanocortin MC4, MC5 and bombesin[3]. | ||||||
| Name | Nemifitide diTFA | ||||||
| CAS | 204992-09-6 | ||||||
| Sequence | {Fluoro-Phe}-{Hyp}-Arg-Gly-Trp-NH2 | ||||||
| Shortening | {Fluoro-Phe}-{Hyp}-RGW-NH2 | ||||||
| Formula | C37H45F7N10O10 | ||||||
| Molar Mass | 922.80 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light) |