| Bioactivity | Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-ALL)[1]. | ||||||||||||
| Invitro | Nelarabine (506U78) (0-20 μM; 48 h) induces cytotoxic effects in T-ALL cell lines[1].Nelarabine (5 or 2 μM; 48 h) promotes apoptosis in sensitive T-ALL cell lines and modulates PI3K/AKT/mTOR and MEK signaling[1].Nelarabine (10 μM; 0-48 h) resistance does not depend on expression of ENT1/2 transporters and is partly due to upregulation of PI3K, MEK, and Bcl2 signaling[1]. Cell Viability Assay[1] Cell Line: | ||||||||||||
| Name | Nelarabine | ||||||||||||
| CAS | 121032-29-9 | ||||||||||||
| Formula | C11H15N5O5 | ||||||||||||
| Molar Mass | 297.27 | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
|
Nelarabine
CAS: 121032-29-9 F: C11H15N5O5 W: 297.27
Nelarabine (506U78) is a nucleoside analogue and can be used for the research of T cell acute lymphoblastic leukemia (T-
Sales Email：peptidedb@qq.com
This product is for research use only, not for human use. We do not sell to patients.