| Bioactivity | Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has the potential for the research of pancreatic cancer[1]. |
| Target | IC50: 15 nM (NEK2) |
| Invitro | Nek2-IN-4 (72 h) 抑制细胞生长，对 AsPC-1、PL45、MIA PaCa-2 细胞的 IC50 值分别为 0.064、0.031、0.161 µM[1]。 Cell Proliferation Assay[1] Cell Line: |
| Name | Nek2-IN-4 |
| CAS | 2225902-88-3 |
| Formula | C28H27F3N6O2S |
| Molar Mass | 568.61 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Hong-Yu Li, et al. Small molecule inhibitors of nek2 and uses thereof. WO2018081719A1. |
Nek2-IN-4
CAS: 2225902-88-3 F: C28H27F3N6O2S W: 568.61
Nek2-IN-4 is a potent NEK2 inhibitor with an IC50 value of 15 nM. Nek2-IN-4 inhibits cell proliferation. Nek2-IN-4 has t
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