| Bioactivity | Navamepent is an analog of naturally occurring resolvin E1 (a major dietary omega-3 polyunsaturated fatty-acid metabolite) with potent anti-inflammatory and cell survival benefits. Navamepent is highly effective against dry eye and goblet cell loss thereby accelerating tear production. Also, Navamepent can reduce corneal inflammation, epithelial damage, and accelerate corneal tissue repair. In addition, Navamepent can inhibit the release of several key proinflammatory mediators from corneal epithelial cells. |
| Name | Navamepent |
| CAS | 1251537-11-7 |
| Formula | C18H24O4 |
| Molar Mass | 304.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Cholkar K, Gilger BC, Mitra AK. Topical delivery of aqueous micellar resolvin E1 analog (RX-10045) [published correction appears in Int J Pharm. 2016 Jul 25;509(1-2):528]. Int J Pharm. 2016;498(1-2):326-334. [2]. Torricelli AA, Santhanam A, Agrawal V, Wilson SE. Resolvin E1 analog RX-10045 0.1% reduces corneal stromal haze in rabbits when applied topically after PRK. Mol Vis. 2014;20:1710-1716. Published 2014 Dec 23. |
Navamepent
CAS: 1251537-11-7 F: C18H24O4 W: 304.38
Navamepent is an analog of naturally occurring resolvin E1 (a major dietary omega-3 polyunsaturated fatty-acid metabolit
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