| Bioactivity | Nav1.7 blocker 1 (example 41) is a Na+ channel (Nav) blocker with an IC50 value of 0.037 μM. Nav1.7 blocker 1 can be used for the study of pain, including neuropathic pain, postoperative pain, inflammatory pain, and so on[1]. |
| Target | IC50: 0.037 μM (sodium channel). |
| CAS | 1426336-36-8 |
| Formula | C22H21FN4O4 |
| Molar Mass | 424.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Chiyou Ni, et al. Pyrimidines as sodium channel blockers. WIPO. Patent. WO2013030665. 2013-03-07 |