Bioactivity | Naphthyridine caebamate dimer (NCD) is a DNA molecular glue that induces designed structural changes in target functional DNA to modulate function[1]. |
Name | Naphthyridine carbamate dimer |
CAS | 864627-58-7 |
Formula | C26H29N7O4 |
Molar Mass | 503.55 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yamada T, et, al. NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA. Nucleic Acids Res. 2022 Sep 23;50(17):9621-9631. [2]. Simeth NA, et, al. Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer. Chem Sci. 2021 May 27;12(26):9207-9220. |