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Naphthyridine carbamate dimer

CAS: 864627-58-7 F: C26H29N7O4 W: 503.55

Naphthyridine caebamate dimer (NCD) is a DNA molecular glue that induces designed structural changes in target functiona
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Bioactivity Naphthyridine caebamate dimer (NCD) is a DNA molecular glue that induces designed structural changes in target functional DNA to modulate function[1].
Name Naphthyridine carbamate dimer
CAS 864627-58-7
Formula C26H29N7O4
Molar Mass 503.55
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Yamada T, et, al. NMR determination of the 2:1 binding complex of naphthyridine carbamate dimer (NCD) and CGG/CGG triad in double-stranded DNA. Nucleic Acids Res. 2022 Sep 23;50(17):9621-9631. [2]. Simeth NA, et, al. Rational design of a photoswitchable DNA glue enabling high regulatory function and supramolecular chirality transfer. Chem Sci. 2021 May 27;12(26):9207-9220.