Nampt activator-4_product_DataBase

CAS: 2847156-05-0 F: C26H22F3N7OS W: 537.56

Nampt activator-4 is a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT) with an E

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	Nampt activator-4 is a positive allosteric modulator (N-PAM) of nicotinamide phosphoribosyltransferase (NAMPT) with an EC50 of 0.058 μM. Nampt activator-4 can enhance the nicotinamide adenine dinucleotide (NAD+) in cells[1].
Target	EC50: 0.058 μM (NAMPT).
Name	Nampt activator-4
CAS	2847156-05-0
Formula	C26H22F3N7OS
Molar Mass	537.56
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Shen,Zhengnan et al. Synthesis, Optimization, and Structure-Activity Relationshipsof Nicotinamide Phosphoribosyltransferase (NAMPT) Positive AllostericModulators (N-PAMs). Journal of medicinal chemistry vol. 66,24 (2023):16704-16727.

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