NaPi2b-IN-2_product_DataBase

CAS: 2227445-31-8 F: C41H47ClF3N5O5S W: 814.36

NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	NaPi2b-IN-2 (compound 5) is a potent inhibitor of sodium-dependent transport protein 2b (SLC34A2, NaPi2b), with an IC50 of 38 nM for human NaPi2b. NaPi2b-IN-2 can be used for the research of hyperphosphatemia[1].
Target	IC50: 38 nM (human NaPi2b)
Name	NaPi2b-IN-2
CAS	2227445-31-8
Formula	C41H47ClF3N5O5S
Molar Mass	814.36
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Ushiki Y, et, al. Design, synthesis and biological evaluation of novel 1H-pyrazole-4-carbonyl-4,5,6,7-tetrahydrobenzo [b]thiophene derivatives as gut-selective NaPi2b inhibitors. Bioorg Med Chem Lett. 2022 Mar 1;59:128572.

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