Bioactivity | Na+-Ca2+ Exchanger inhibitory peptide (XIP) is a Na+-Ca2+ exchanger inhibitor with a Ki of 200 nM. Na+-Ca2+ Exchanger inhibitory peptide inhibits the Na+-dependent Ca2+ uptake and the Na+-dependent Ca2+ efflux of sarcolemmal vesicles in a noncompetitive manner[1]. |
Sequence | Arg-Arg-Leu-Leu-Phe-Tyr-Lys-Tyr-Val-Tyr-Glu-Tyr-Glu-Ala-Gly-Glu-Gln-Glu-Gly |
Shortening | RRLLFYKYVYEYEAGEQEG |
Formula | C112H161N27O33 |
Molar Mass | 2413.64 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Z Li, et al. Identification of a peptide inhibitor of the cardiac sarcolemmal Na(+)-Ca2+ exchanger. J Biol Chem. 1991 Jan 15;266(2):1014-20. |