Bioactivity | NY-ESO-1 (157–165) peptide is a peptide fragment from NY-ESO-1 protein. NY-ESO-1 (157–165) peptide can activate the immune system, especially for HLA-A2 positive individuals, it can be recognized by CD8+ T cells, thus triggering an immune response. HLA-A2 is a class I major histocompatibility complex (MHC) allele belonging to the HLA-A group of human major histocompatibility complex (MHC) leukocyte antigens (HLA). HLA-A is a human MHC class I cell surface receptor involved in presenting short peptides to the immune system. NY-ESO-1 (157–165) peptide is expressed in a variety of tumors and can be used as a target for tumor immunotherapy. NY-ESO-1 (157–165) peptide can be used in the study of cancer immunotherapy[1]. |
CAS | 202815-17-6 |
Sequence | Ser-Leu-Leu-Met-Trp-Ile-Thr-Gln-Cys |
Shortening | SLLMWITQC |
Formula | C49H79N11O13S2 |
Molar Mass | 1094.35 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Davis I D, et al. Recombinant NY-ESO-1 protein with ISCOMATRIX adjuvant induces broad integrated antibody and CD4+ and CD8+ T cell responses in humans[J]. Proceedings of the National Academy of Sciences, 2004, 101(29): 10697-10702. |