Bioactivity | NU074381b (compound 5b) is a potent S100A4 inhibitor. NU074381b inhibits S100A4-NMII complex formation with an IC50 value of 0.48 µM. NU074381b inhibits cell proliferation and migration[1]. |
Invitro | NU074381b 通过与半胱氨酸 81 特异性反应共价抑制 S100A4[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> NU074381b 相关抗体: |
Formula | C23H25ClN2O2 |
Molar Mass | 396.91 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Giroud C, et al. Covalent Inhibitors of S100A4 Block the Formation of a Pro-Metastasis Non-Muscle Myosin 2A Complex. J Med Chem. 2024 Oct 19. |