| Bioactivity | NSC363998 (free base) is an orally active compound. NSC363998 (free base) can suppress rCGG90 induced neurotoxicity. NSC363998 (free base) can be used for the research of neurodegenerative disorder such as Fragile X associated tremor/ataxia syndrome (FXTAS)[1]. |
| In Vivo | NSC363998 (free base) (oral; 0, 5 μM) can suppress rCGG90 induced neurotoxicity[1]. Animal Model: |
| Name | NSC363998 free base |
| CAS | 159357-82-1 |
| Formula | C24H32N4O4 |
| Molar Mass | 440.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yunting Lin, et al. Neddylation activity modulates the neurodegeneration associated with fragile X associated tremor/ataxia syndrome (FXTAS) through regulating Sima. Neurobiol Dis. 2020 Sep;143:105013. |