| Bioactivity | NSC309401 is an inhibitor of E. coli DHFR (IC50: 189 nM, KD: 14.57 nM)[1]. |
| Target | 189 nM (E. coli DHFR). |
| Name | NSC309401 |
| CAS | 750522-61-3 |
| Formula | C17H16N6 |
| Molar Mass | 304.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Srinivasan B, et al. Insights into the slow-onset tight-binding inhibition of Escherichia coli dihydrofolate reductase: detailed mechanistic characterization of pyrrolo [3,2-f] quinazoline-1,3-diamine and its derivatives as novel tight-binding inhibitors. FEBS J. 2015 May;282(10):1922-38. |