| Bioactivity | NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has anticancer activity[1]. |
| Invitro | NSC243928 mesylate (2 μM, 24 h) 可以诱导 MDA-MB-231 对照细胞死亡，而在 LY6K 敲低细胞中显示细胞活力增加，进而表明 NSC243928 可能通过 LY6K 途径诱导细胞死亡[1]。NSC243928 mesylate 作用于MDA-MB-231，Hs-578-T，BT-549，OVCAR-8 细胞的 IC50 值分别是 5.683 μM，7.309 μM，7.954 μM 和 4.167 μM[1]。 |
| Name | NSC243928 mesylate |
| CAS | 59988-01-1 |
| Formula | C23H25N3O6S2 |
| Molar Mass | 503.59 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Senyi Benti, et al. Small Molecule Binds with Lymphocyte Antigen 6K to Induce Cancer Cell Death. Cancers (Basel). 2020 Feb 22;12(2):509. |
NSC243928 mesylate
CAS: 59988-01-1 F: C23H25N3O6S2 W: 503.59
NSC243928 mesylate is a human lymphocyte antigen 6 (LY6) binder, which also acts as an inhibitor of cell growth and has
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