| Bioactivity | NS5818 is a potent chloride channel inhibitor. NS5818 inhibits acidification and bone resorption. NS5818 has the potential for the research of osteoporosis[1]. |
| Invitro | NS5818 (50 µM; 6 days) 可抑制破骨细胞吸收区室的酸化和骨吸收，对人类破骨细胞骨吸收的 IC50 值为 5µM[1]。NS5818 (10 µM; 20 days) 可抑制在牛骨切片上培养的成熟破骨细胞的骨吸收[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> NS5818 相关抗体: |
| CAS | 674299-39-9 |
| Formula | C23H19Cl2N7O2 |
| Molar Mass | 496.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Karsdal MA, et al. Acidification of the osteoclastic resorption compartment provides insight into the coupling of bone formation to bone resorption. Am J Pathol. 2005 Feb;166(2):467-76. |
NS5818
CAS: 674299-39-9 F: C23H19Cl2N7O2 W: 496.35
NS5818 is a potent chloride channel inhibitor. NS5818 inhibits acidification and bone resorption. NS5818 has the potenti
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