| Bioactivity | NRPSs-IN-1 (Compound 7) is a cell-penetrating inhibitor of non-ribosomal peptide synthetase (NRPSs). NRPSs-IN-1 K inhibits gramicidin S synthetase A (GrsA) with a Kd value of 16.6 nM[1]. |
| Target | non-ribosomal peptide synthetases (NRPSs) |
| Invitro | NRPSs-IN-1 (10 µM) 有效抑制 ABP ʟ-Phe-AMS-BPyne 标记 GrsA[1]。 MCE has not independently confirmed the accuracy of these methods. They are for reference only. 0 --> NRPSs-IN-1 相关抗体: |
| Formula | C22H25N7O7S |
| Molar Mass | 531.54 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Ishikawa F, et al. Development of a chemical scaffold for inhibiting nonribosomal peptide synthetases in live bacterial cells. Beilstein J Org Chem. 2024 Feb 26;20:445-451. |