Bioactivity | NRMA-8 is a brain-penetrant small molecule nuclear receptor modulator. NRMA-8 is promising for research of central nervous system disorders, including Alzheimer's disease, Parkinson's disease, demylenation disorders and glioblastomas[1][2]. |
CAS | 2375659-15-5 |
Formula | C20H23ClN2O3 |
Molar Mass | 374.86 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. SCANLAN Thomas S, et al. N-methyl amide prodrugs of small molecule nuclear receptor modulators. WO2019168842. 2018 March 02. [2]. Ferrara SJ, et al. A CNS-Targeting Prodrug Strategy for Nuclear Receptor Modulators. J Med Chem. 2020 Sep 10;63(17):9742-9751. |