NR2B-selective NMDA receptor antagonist 1_product_DataBase

CAS: 457897-92-6 F: C18H22Cl2N2O4S W: 433.35

NR2B-selective NMDA receptor antagonist 1 (compound 29) is a potent antagonist of NR1/NR2B receptors, with IC50s of 0.05

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	NR2B-selective NMDA receptor antagonist 1 (compound 29) is a potent antagonist of NR1/NR2B receptors, with IC50s of 0.05 μM, 0.73 μM, 2.4 μM to NR1/NR2B NMDA receptor, hERG, α1-AdR, respectivity. NR2B-selective NMDA receptor antagonist 1 exhibites efficient permeability across the blood–brain barrier[1].
CAS	457897-92-6
Formula	C18H22Cl2N2O4S
Molar Mass	433.35
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Yesim A Tahirovic, et al. Enantiomeric Propanolamines as selective N-Methyl-D-aspartate 2B Receptor Antagonists. J Med Chem. 2008 Sep 25;51(18):5506-21.

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