NOX2-IN-2_product_DataBase

CAS: 2648709-79-7 F: C25H25N7O3 W: 471.51

NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki o

This product is for research use only, not for human use. We do not sell to patients.

Bioactivity	NOX2-IN-2 (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 inhibits ROS production derived from NOX2 in cells[1].
Name	NOX2-IN-2
CAS	2648709-79-7
Formula	C25H25N7O3
Molar Mass	471.51
Transport	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Reference	[1]. Jie Zang, et al.Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors. J Med Chem. 2023 Oct 19.

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