| Bioactivity | NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with a Ki of 0.24 μM. NOX2-IN-2 diTFA inhibits ROS production derived from NOX2 in cells[1]. |
| CAS | 2648709-80-0 |
| Formula | C29H27F6N7O7 |
| Molar Mass | 699.56 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Jie Zang, et al.Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors. J Med Chem. 2023 Oct 19. |
NOX2-IN-2 diTFA
CAS: 2648709-80-0 F: C29H27F6N7O7 W: 699.56
NOX2-IN-2 diTFA (compound 33) is a potent NOX2 inhibitor targeting the p47phox-p22phox protein-protein interaction with
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