Bioactivity | NOTA-P2-RM26 is an antagonist of Bombesin (HY-P0195) analogs, and the gastrin-releasing peptide receptor (GRPR/BB2) is a molecular target for prostate cancer visualization. NOTA-P2-RM26 is labeled with 111In and 68Ga for prostate cancer imaging studies using PET and SPECT/CT[1]. |
CAS | 1446005-10-2 |
Sequence | {NOTA}-{D-Phe}-GlnTrp-Ala-Val-Gly-His-{Sta}-Leu-NH2 |
Shortening | {NOTA}-{D-Phe}-QWAVGH-{Sta}-L-NH2 |
Formula | C73H110N18O19 |
Molar Mass | 1543.76 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Varasteh Z, et al. Synthesis and characterization of a high-affinity NOTA-conjugated bombesin antagonist for GRPR-targeted tumor imaging. Bioconjug Chem. 2013 Jul 17;24(7):1144-53. |