| Bioactivity | NODAGA-NHS (NODA-GA-NHS ester) is a [64]Cu chelator and the dissociated form of DOTA-trastuzumab in vivo. NODAGA-NHS was added in 0.1 M borate buffer at a ratio of 5/20/100 and was able to effectively bind trastuzumab (10 mg/mL) (4°C, 20 h). The copper content of the [64]Cu-NODAGA-trastuzumab was up to 80%. After blood was drawn from the caudal vein of mice, [64]Cu-NODAGA-trastuzumab was injected and showed good tumor uptake in mice expressing HER2 tumors, showing good PET imaging tracking ability. |
| CAS | 1407166-70-4 |
| Formula | C19H28N4O10 |
| Molar Mass | 472.45 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
NODAGA-NHS
CAS: 1407166-70-4 F: C19H28N4O10 W: 472.45
NODAGA-NHS (NODA-GA-NHS ester) is a Cu chelator and the dissociated form of DOTA-trastuzumab in vivo. NODAGA-NHS was add
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