| Bioactivity | NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total soluble Aβ42, increases brain neprilysin activity and improves learning[1][2]. |
| Name | NNC 26-9100 |
| CAS | 199522-35-5 |
| Formula | C22H25BrCl2N6S |
| Molar Mass | 556.35 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Michael Ankersen, et al. Discovery of a Novel Non-Peptide Somatostatin Agonist with SST4 Selectivity. J. Am. Chem. Soc. 1998, 120, 7, 1368-1373. [2]. Sandoval KE, et al. Somatostatin receptor subtype-4 agonist NNC 26-9100 mitigates the effect of soluble Aβ(42) oligomers via a metalloproteinase-dependent mechanism. Brain Res. 2013 Jul 3;1520:145-56. |
NNC 26-9100
CAS: 199522-35-5 F: C22H25BrCl2N6S W: 556.35
NNC 26-9100 is a selective somatostatin sst4 receptor full agonist (Ki: 6 nM, EC50: 2 nM). NNC 26-9100 decreases total s
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