| Bioactivity | NNC-0640 is a potent human G-protein-coupled glucagon receptor (GCGR) negative allosteric modulator (NAM) with an IC50 of 69.2 nM[1]. | ||||||||||||
| Target | Human Glucagon Receptor | ||||||||||||
| Name | NNC-0640 | ||||||||||||
| CAS | 307986-98-7 | ||||||||||||
| Formula | C29H31N7O4S | ||||||||||||
| Molar Mass | 573.67 | ||||||||||||
| Appearance | Solid | ||||||||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||||||||
| Storage |
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| Reference | [1]. Zhang H, et al. Structure of the full-length glucagon class B G-protein-coupled receptor. Nature. 2017 Jun 8;546(7657):259-264. |