Bioactivity | NMDA receptor antagonist 6 (compound 13b) is an antagonist of NMDA receptor, targeting to the glycine binding site. NMDA receptor antagonist 6 shows cytoneuroprotective potency, and protects PC12 cells against NMDA-induced injury and cell apoptosis[1]. |
Target | NMDA receptor |
Name | NMDA receptor antagonist 6 |
Formula | C25H23NO2 |
Molar Mass | 369.46 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Yang L, et al. Design, synthesis and evaluation of novel 1-phenyl-pyrrolo [1, 2-b] isoquinolin-3-one derivatives as antagonists for the glycine binding site of the NMDA receptor[J]. European Journal of Medicinal Chemistry, 2023: 115624. |