| Bioactivity | NLS-StAx-h TFA is a selective, cell permeable, stapled peptide Wnt signaling inhibitor with an IC50 of 1.4 μM. NLS-StAx-h TFA efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h TFA shows anti-proliferation of cancer cells[1][2]. | ||||||
| Invitro | NLS-StAx-h (10 μM; 72 h) inhibits proliferation of colorectal cancer cells[1].NLS-StAx-h (5 and 10 μM; 24 h) inhibits migration of colorectal cancer cells[1]. Cell Proliferation Assay[1] Cell Line: | ||||||
| Name | NLS-StAx-h TFA | ||||||
| Formula | C162H276F3N55O31 | ||||||
| Molar Mass | 3559.28 | ||||||
| Transport | Room temperature in continental US; may vary elsewhere. | ||||||
| Storage | Sealed storage, away from moisture and light, under nitrogen
*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen) |