| Bioactivity | NLRP3-IN-62 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-62 inhibits pyroptosis in THP-1 cell with an IC50 of 0.7 nM, inhibits IL-β release with an IC50 of 108.5 nM[1]. |
| CAS | 3059965-71-5 |
| Formula | C21H15F3N4O3 |
| Molar Mass | 428.36 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. AITKEN LS, et al., Nlrp3 inhibitors. WO2024213552. |
NLRP3-IN-62
CAS: 3059965-71-5 F: C21H15F3N4O3 W: 428.36
NLRP3-IN-62 (Compound 1) is an inhibitor for NLRP3. NLRP3-IN-62 inhibits pyroptosis in THP-1 cell with an IC50 of 0.7 nM
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