| Bioactivity | NLRP3-IN-56 (compound 062) is a NLRP3 inhibitor. NLRP3-IN-56 potently inhibits the level of IL-1β secretion by THP-1 cells with an IC50 of 9.7 nM. NLRP3-IN-56 can be used for the study of NLRP3-mediated symptoms and/or diseases[1]. |
| CAS | 3048421-42-4 |
| Formula | C20H18ClN3O3 |
| Molar Mass | 383.83 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Fanglong Yang, et al. Pyridazine nlrp3 inhibitor compound, pharmaceutical composition, and preparation method therefor and use thereof. WO2024140824A1. |
NLRP3-IN-56
CAS: 3048421-42-4 F: C20H18ClN3O3 W: 383.83
NLRP3-IN-56 (compound 062) is a NLRP3 inhibitor. NLRP3-IN-56 potently inhibits the level of IL-1β secretion by THP-1 ce
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