Bioactivity | NLRP3-IN-37 (Compound 23) is a NLRP3 inhibitor (EC50: 5 nM). NLRP3-IN-37 can be used for NLRP3 related research, such as gout, pseudogout, CAPS, NASH fibrosis, heart failure, idiophathic pericarditis, atopic dermatitis, inflammatory bowel disease, Alzheimer's Disease, Parkinson's Disease and traumatic brain injury[1]. |
CAS | 3033054-51-9 |
Formula | C22H22F3N5O |
Molar Mass | 429.44 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Donna A. A, et al. WPhthalazine derivatives useful as inhibitors of nod-like receptor protein 3. Patent.WO2024064245A1. |