| Bioactivity | NLRP3-IN-29(Compound 5M) is an inhibitor of NLR family pyrin domain containing 3 (NLRP3). NLRP3-IN-29 has the potential for blood-brain barrier permeability and inflammation inhibition both in vivo and in vitro. NLRP3-IN-29 can be used for research on Alzheimer's disease[1]. |
| Name | NLRP3-IN-29 |
| CAS | 2198483-40-6 |
| Formula | C21H22N2O3S |
| Molar Mass | 382.48 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Kim EY, et al. Structure-based design and synthesis of sulfonylureas as novel NLRP3 inhibitors for Alzheimer's disease. Bioorg Med Chem Lett. 2024 Jan 19;99:129622. |
NLRP3-IN-29
CAS: 2198483-40-6 F: C21H22N2O3S W: 382.48
NLRP3-IN-29(Compound 5M) is an inhibitor of NLR family pyrin domain containing 3 (NLRP3). NLRP3-IN-29 has the potential
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