| Bioactivity | NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity for NLRP3 with an IC50 value of ＜0.3 μM. NLRP3-IN-11 can be used for the researh of inflammatory and degenerative diseases including NASH, atherosclerosis and other cardiovascular diseases, Alzheimer's disease, Parkinson's disease, diabetes, gout, and numerous other autoinflammatory diseases[1]. |
| Invitro | NLRP3-IN-11 has biological activity with an IC50 value of ＜0.3 μM in human PBMC NLRP3 assay[1] |
| Name | NLRP3-IN-11 |
| CAS | 2769040-91-5 |
| Formula | C17H17ClN4O2 |
| Molar Mass | 344.80 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. HY-W048205, et al. Compounds for inhibiting NLRP3 and uses thereof. Patent. US11319319B1. |
NLRP3-IN-11
CAS: 2769040-91-5 F: C17H17ClN4O2 W: 344.80
NLRP3-IN-11 is a NLR family pyrin domain containing 3 (NLRP3) proteins inhibitor. NLRP3-IN-11 has biological activity fo
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