PeptideDB

NK3R-IN-1

CAS: 2854331-14-7 F: C17H16FN5OS W: 357.41

NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R
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Bioactivity NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model[1].
Name NK3R-IN-1
CAS 2854331-14-7
Formula C17H16FN5OS
Molar Mass 357.41
Transport Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Reference [1]. Ye L, et al. Synthesis and evaluation of piperazinotriazoles. Discovery of a potent and orally bioavailable neurokinin-3 receptor inhibitor. Eur J Med Chem. 2023 Sep 5;257:115486.