| Bioactivity | NIR-FP is a near-infrared fluorescent probe with high sensitivity and selectivity for superoxide anion O2?-. O2?- is the main precursor of ROS, and ferroptosis-mediated epilepsy models can be dynamically tracked by detecting O2?-. Ferroptosis-mediated epilepsy models include: kainic acid (HY-N2309)-induced chronic epilepsy model, Pentylenetetrazole-induced acute epilepsy model, and pilocarpine (HY-B0726A)-induced epilepsy model[1]. |
| Target | Superoxide anion (O2?-) |
| Name | NIR-FP |
| Formula | C20H17F3N2O3S |
| Molar Mass | 422.42 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Yang W, et al. Novel Near-Infrared Fluorescence Probe for Bioimaging and Evaluating Superoxide Anion Fluctuations in Ferroptosis-Mediated Epilepsy. Anal Chem. 2023 Aug 22;95(33):12240-12246.. |