Bioactivity | NIOCH 14 is a antiviral agent and a pro-drug. NIOCH 14 has antiviral activity against orthopoxviruses. NIOCH 14 can significantly lower proportions of infected mice, and virus production levels in the lungs. NIOCH 14 can be used for researching anti-smallpox[1][2]. NIOCH 14 shows anti-orthopoxvirus activity. |
Target | Orthopoxviruses |
Name | NIOCH 14 |
CAS | 1268015-38-8 |
Formula | C19H17F3N2O4 |
Molar Mass | 394.34 |
Transport | Room temperature in continental US; may vary elsewhere. |
Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
Reference | [1]. Sokolova AS, et al. (+)-Camphor and (-)-borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim). 2021;354(6):e2100038. [2]. Mazurkov OY, et al. New effective chemically synthesized anti-smallpox compound NIOCH-14. J Gen Virol. 2016;97(5):1229-1239. [3]. Anastasiya S Sokolova, et al. (+)-Camphor and (-)-borneol derivatives as potential anti-orthopoxvirus agents. Arch Pharm (Weinheim). 2021 Jun;354(6):e2100038. |