| Bioactivity | NIBR-LTSi is a selective LATS kinase inhibitor and activates YAP signaling. NIBR-LTSi promotes proliferation, maintains stemness, and blocks differentiation. NIBR-LTSi accelerates liver regeneration, following partial and extended hepatectomy[1]. |
| Formula | C18H20N4O |
| Molar Mass | 308.38 |
| Transport | Room temperature in continental US; may vary elsewhere. |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Reference | [1]. Namoto K, et al. NIBR-LTSi is a selective LATS kinase inhibitor activating YAP signaling and expanding tissue stem cells in vitro and in vivo. Cell Stem Cell. 2024 Apr 4;31(4):554-569.e17. |